In this article, we'll explore the health benefits of palmitoylethanolamide acid, its dietary sources, potential side effects, and how to choose the right PEA dietary supplement to meet your needs. We will also examine its therapeutic applications. Good reading !
The health benefits of palmitoylethanolamide acid (PEA).
Palmitoylethanolamide acid (PEA) is considered to have anti-inflammatory properties , and it has been studied for its potential in the treatment of various conditions.
Studies have suggested that PEA may be beneficial in treating certain conditions such as:
- Chronic pain : PEA may regulate inflammatory and analgesic responses, which may help relieve chronic pain associated with various conditions, such as osteoarthritis and fibromyalgia.
- Neuropathy : PEA may improve symptoms of neuropathy, a condition characterized by nerve pain.
- Inflammation : PEA may regulate inflammatory responses by modulating the production of pro-inflammatory cytokines, which may be beneficial in the treatment of various conditions associated with inflammation, such as autoimmune diseases.
- Depression and anxiety : Studies have shown that PEA can regulate emotional responses by acting on receptors involved in pain transmission, which may be beneficial in relieving symptoms of anxiety and depression.
There are obviously other plants or extracts which can have anti-inflammatory actions. Such as Turmeric capsules, Blackcurrant buds .
When to use palmitoylethanolamide acid (PEA)?
The use of palmitoylethanolamide acid (PEA) may be useful in the support or management of various diseases and pathologies, including:
- Chronic pain , including neuropathic pain, pain associated with arthritis, fibromyalgia, low back pain and other conditions.
- Inflammation and inflammatory disorders such as colitis, Crohn's disease, asthma and rheumatoid arthritis.
- Neurological disorders , including peripheral neuropathy, diabetic neuropathy, multiple sclerosis and Parkinson's disease.
- Autoimmune diseases , such as lupus, multiple sclerosis and rheumatoid arthritis.
- Mood disorders, including depression and anxiety.
- Allergies and allergic disorders such as asthma and eczema.
It is important to note that palmitoylethanolamide acid should not be used as the primary treatment for these conditions, but rather as an adjunct to appropriate medical treatment.
PEA, palmitoylethanolamide acid, what is it?
Palmitoylethanolamide acid (PEA) is a compound naturally produced in the human body in response to signals of pain and inflammation. It belongs to a class of compounds called " endocannabinoids ", which are chemical messengers involved in various biological processes such as pain, inflammation, the immune system and metabolism. Although palmitoylethanolamide acid is an endocannabinoid, it does not bind directly to cannabinoid receptors.
Palmitoylethanolamide acid is produced from palmitic acid, a saturated fatty acid found in animal and plant foods. It is also found in some foods, including egg yolks, soy, peanut butter, and breast milk.
Palmitoylethanolamide acid has anti-inflammatory and analgesic effects and may help reduce pain and inflammation. It can also be used to treat conditions such as peripheral neuropathy, chronic pain, osteoarthritis, fibromyalgia, and other inflammatory disorders.
Although palmitoylethanolamide acid is produced naturally in the body, its production may be insufficient to respond to high levels of pain or inflammation. In these cases, supplementation with palmitoylethanolamide acid may be beneficial.
Who discovered palmitoylethanolamide acid or pea?
Palmitoylethanolamide acid (PEA) was first discovered in the 1950s. Italian researchers identified this compound as a breakdown product of the saturated fatty acid called palmitic acid. Since then, numerous studies have been carried out to study the properties and effects of PEA on health.
PEA was initially considered to be a secondary mediator in the nervous system and the immune system. Over the years, new research has revealed that PEA may also act as an anti-inflammatory, analgesic, and modulator of emotional responses.
In conclusion, the discovery of PEA was an important step in understanding the biology of endocannabinoid lipids and their role in health. Recent advances in PEA extraction and purification techniques have enabled the development of PEA-based dietary supplements to support health.
What are the food sources of palmitoylethanolamide acid (PEA)?
Palmitoylethanolamide acid (PEA) is a substance produced naturally by the human body. However, it is also present in some foods in small amounts. Here are some food sources of PEA:
- Eggs : egg yolks contain PEA.
- Breast milk : Breast milk contains high amounts of PEA, which may explain some of the health benefits for breastfed infants.
- Peanuts : Peanuts are a dietary source of PEA.
- Yeasts : some yeasts, such as brewer's yeast, also contain PEA.
However, it is important to note that the amount of PEA found in these foods is generally low and can vary widely. Therefore, consuming foods containing PEA in normal amounts is unlikely to have a significant effect on PEA levels in the body.
PEA, how is it made and how to choose the right supplement?
Food supplements based on palmitoylethanolamide acid (PEA) are generally made from natural sources such as palm trees used to make palm oil, soybeans or brown rice using a process called Ultra Micronization.
The PEA molecule is extracted from these sources and purified to obtain a pharmaceutical grade product.
The production process varies depending on the supplier, but it generally involves the following steps:
- Extraction : The PEA molecule is extracted from the natural source using ultrasound
- Purification : The resulting solution is purified to remove impurities and obtain a pharmaceutical quality product.
- Formulation : The PEA molecule is then formulated into tablets or capsules, depending on the supplier's preferences.
- Quality control : Before being placed on the market, PEA-based dietary supplements undergo quality control testing to ensure their safety and effectiveness.
The best quality you can find on the market is the Opti PEA technology with which Vit'all+ works.
OptiPEA is a technology for producing food supplements based on palmitoylethanolamide acid (PEA). This is a specific production process designed to produce dietary supplements of superior quality in terms of purity, stability and effectiveness. for people wanting to get the most out of the anti-inflammatory and analgesic properties of PEA.
OptiPEA uses a multi-step purification process to produce premium PEA. This process includes filtration, chromatography and distillation steps to remove impurities and ensure the purity of the final product.
Additionally, OptiPEA uses a micronized form of PEA to improve the absorption and bioavailability of the product. The micronized form of PEA is smaller than conventional particles, so it is a liposome, which facilitates its passage through cell membranes and increases its absorption by the body.
Finally, OptiPEA uses a stabilized form of PEA to ensure product stability during storage and shelf life. The stabilized form of PEA is designed to resist oxidation and degradation, ensuring the product's effectiveness throughout its lifespan.
It is important to note that the quality of PEA-based food supplements can vary considerably depending on the supplier, and it is always advisable to choose products manufactured by reliable, quality companies such as Vit'All+.
PEA-400mg-30 capsules-Vit'all+
Are there any side or adverse effects of palmitoylethanolamide acid (PEA) supplementation?
Studies have shown that palmitoylethanolamide acid (PEA) supplementation is generally well tolerated and does not cause serious side effects. However, as with any supplement, side effects may occur in some people, although this is rare.
The most common side effects associated with PEA supplementation are gastrointestinal problems, diarrhea, or constipation, similar to marine magnesium.
It is important to note that if you are taking medication or suffering from a medical condition, it is recommended that you consult your doctor, or ask us before taking a PEA supplement or any other nutritional supplement.
In summary, PEA supplementation is generally considered safe, but as with any supplement, it is important to follow recommended doses.
Comments (14)
Bonjour,
Je voudrais savoir s’il on peut prendre du PEA pour des douleurs articulaires. Sous traitement FEMARA pour un cancer du sein hormo dépendant
Y a t il des interactions ?
Merci à vous
Isabelle
Bonjour peut on donner le PEA à un chien de 14 ans et 25 kg qui est en bonne santé mais qui a de l’arthrose. Merci d’avance pour votre réponse
Bonjour Me Barat
Nous n’avons malheureusement pas de retour concret sur ce sujet, il est préférable de demandé l’avis du médecin ou d’appeler directement Vit’all+ (02 43 39 97 27) pour plus de renseignements. A l’heure actuelle il n’y pas de contre indications sur se sujet.
Bonjour, Puis-je l’associer avec du méthotrexate 15 mg/ SEMAINE ?
Merci pour votre réponse.
Bonjour Mr Stadler
Il n’y a pas de contre indications concernant l’insuffisance rénale sur le Pea de chez Vit’all+
Bonjour,
Très intéressé par le PEA, je voudrais savoir si pour l’insuffisance rénale, il y a une contre indication, malheureusement mon médecin ne connaît pas et ne veut pas se prononcer !
Merci pour votre réponse.
JP S
Bonjour Mme Legrand,
1. PEA et corticoïdes, Ventoline et Atrovent:
D’après les informations disponibles, il n’y a pas d’interactions médicamenteuses connues entre le PEA et les corticoïdes, la Ventoline (salbutamol) ou l’Atrovent (ipratropium) en nébulisation.
Cependant, il est toujours recommandé de consulter votre médecin ou un pharmacien avant de prendre tout nouveau complément alimentaire, en particulier si vous avez des problèmes de santé préexistants ou si vous prenez d’autres médicaments.
Votre médecin pourra évaluer votre situation individuelle et vous conseiller sur la pertinence et la posologie adéquate du PEA en association avec vos traitements actuels.
2. PEA et coxarthrose:
Les études sur l’efficacité du PEA pour soulager la coxarthrose sont encore limitées.
Certaines recherches suggèrent des effets potentiellement bénéfiques, mais des preuves plus solides sont nécessaires pour confirmer son efficacité et son innocuité dans cette indication.
Il est important de discuter de cette option avec votre médecin avant de commencer à prendre du PEA pour la coxarthrose. Il pourra vous aider à évaluer les risques et les avantages potentiels et vous orienter vers d’autres options thérapeutiques si nécessaire.
3. PEA et huile de palme:
Le PEA peut effectivement être extrait de l’huile de palme.
Cependant, il est important de noter que d’autres sources végétales de PEA existent également.
La consommation d’huile de palme est controversée en raison de ses effets potentiels sur la santé cardiovasculaire.
Si vous êtes préoccupée par l’origine du PEA, vous pouvez opter pour des compléments dérivés d’autres sources végétales.
4. PEA et acides gras:
Le PEA n’est pas un acide gras insaturé.
Il s’agit plutôt d’un amide d’acide gras, une molécule distincte avec ses propres propriétés.
En résumé:
Le PEA peut être pris sans interaction connue avec les corticoïdes, la Ventoline et l’Atrovent, mais il est toujours conseillé de consulter un professionnel de santé avant de l’utiliser.
Les preuves sur l’efficacité du PEA pour la coxarthrose sont limitées et nécessitent des recherches plus approfondies.
Le PEA peut être extrait de l’huile de palme, mais d’autres sources végétales existent.
Le PEA n’est pas un acide gras insaturé.
J’espère que ces informations vous sont utiles. N’hésitez pas à me contacter si vous avez d’autres questions.
Cordialement,
Bonjour Me Joly
D’après les recherches actuelles :
La posologie recommandée pour la fibromyalgie se situe entre 400 et 1200 mg par jour, répartie en plusieurs prises dans la journée.
Il est conseillé de commencer par une dose faible (autour de 400 mg) et d’augmenter progressivement si nécessaire, en fonction de votre réponse au traitement.
Il est important de respecter les instructions posologiques indiquées sur l’emballage du produit que vous utilisez.
Durée du traitement :
Le PEA peut être pris sur une longue durée, plusieurs mois voire plusieurs années, si nécessaire.
Il n’y a pas de limite de temps maximale d’utilisation.
Il est important de faire des pauses régulièrement, par exemple une semaine toutes les 6 à 8 semaines, pour évaluer l’efficacité du traitement et s’assurer qu’il n’y a pas d’effets secondaires.
Compatibilité avec le Levothyrox :
A ce jour, aucune interaction médicamenteuse n’a été rapportée entre le PEA et le Levothyrox.
Il est néanmoins toujours recommandé d’en parler à votre médecin avant de commencer à prendre un nouveau complément alimentaire, en particulier si vous prenez des médicaments, y compris le Levothyrox.
Bonjour, le pea pour la fibromyalgie, quelle posologie et peut on le prendre au long cours. Je prends du Levothyrox est ce compatible ? Merci
Bonjour Me Angles,
il n’y a pas de problèmes à prendre du PEA sur des cures longues, même si une pause de temps en temps permettra au corps de se situé face à la douleur. Je vous est mis plus de précision dans un mail dédié.
Belle journée