Organic Shiitake — Immunostimulant with Beta-Glucans and Lentinan, 20 Ampoules of 10ml

The most consumed immune-supporting mushroom in the world in a bioavailable format with Biotechnie Organic Shiitake: 20 ampoules of 10ml of organic Lentinula edodes juice, extracted using the patented Biotechnie fermentation method. Rich in lentinan and beta-glucans to strengthen natural defenses, support metabolic balance, and protect cells from oxidative aging. Liquid format for immediate absorption.

Why is shiitake one of the most well-documented immunostimulants?

Shiitake (Lentinula edodes) owes its immunostimulant properties to two categories of active ingredients: lentinan (a specific beta-1,3-glucan, the first mushroom active ingredient to receive marketing authorization in Japan as an adjuvant immunostimulant for oncological therapies) and general polysaccharide beta-glucans. These molecules bind to Dectin-1 receptors on macrophages and NK (Natural Killer) cells, triggering an immune activation cascade: increased phagocytosis, stimulation of interleukin production (IL-2, IL-6, IL-12) and interferon gamma, and activation of cytotoxic T lymphocytes. Shiitake also contains eritadenine, a unique compound that inhibits cholesterol biosynthesis and contributes to a balanced lipid profile. Its richness in erythritol, vitamins B2, B5, D2, and zinc completes its overall health action.

Benefits of Biotechnie Shiitake

• Powerful stimulation of innate and adaptive immunity: Lentinan and beta-glucans activate macrophages, NK cells, and T lymphocytes for a faster and more effective immune response against infections. Randomized clinical studies have shown a reduction in the duration and intensity of infectious episodes (colds, flu) after 4 weeks of shiitake supplementation.
• Support for metabolic balance and cholesterol: Shiitake's eritadenine inhibits the COMT (catechol-O-methyltransferase) enzyme involved in homocysteine metabolism and the cholesterol biosynthesis enzyme. Animal and preliminary human studies show a reduction in LDL cholesterol and an improvement in the LDL/HDL ratio after supplementation.
• Cellular antioxidant protection: Shiitake is rich in ergothioneine, a natural sulfur-containing antioxidant that accumulates specifically in cells exposed to oxidative stress (erythrocytes, liver, kidneys, brain). Ergothioneine is considered one of the most powerful cellular antioxidants known, with a long half-life and high intracellular concentration.
• Natural vitamin D2 intake: Shiitake exposed to the sun naturally produces vitamin D2 (ergocalciferol). Although less effective than D3, it contributes to the maintenance of the immune system and bone health. The Biotechnie liquid format preserves this fragile vitamin better than dried forms.

Composition

Extracted using the patented Biotechnie fermentation method. 100% certified organic. 20 ampoules of 10ml.

Who is this supplement for?

• People prone to repeated ENT infections (colds, sore throats, ear infections) wishing to strengthen their baseline immunity
• The elderly whose immunity naturally declines with age (immunosenescence)
• People wishing to support their lipid balance naturally as a complement to a suitable diet
• People in convalescence or in a post-infectious recovery period

Dosage

1 ampoule per day, preferably in the morning, in a glass of water. 20-day course. Can be renewed for winter prevention (October-November) and in the spring.

Precautions and contraindications

• Mushroom allergy: Contraindicated in case of allergy to mushrooms or mold.
• Immunosuppressants: The immunostimulant action of shiitake can theoretically interact with immunosuppressants (cyclosporine, tacrolimus, long-term corticosteroids) — consult a doctor before use.
• Autoimmune diseases: As a precaution, people with autoimmune diseases (lupus, rheumatoid arthritis, multiple sclerosis) should consult a doctor before use.
• Pregnant or breastfeeding women: Not recommended as a precaution (insufficient data).
• Keep out of reach of children. Do not exceed the daily dose.

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To learn more: Read the article The health benefits of Shiitake